[NMR] Career Opportunities at AI|ffinity: AI meets NMR in Structural Biology and Drug Design

We are excited to announce career opportunities at AI|ffinity, a company that combines the power of Artificial Intelligence 🧠 with Nuclear Magnetic Resonance 🧲 to reshape the structural biology landscape and steer the future of drug discovery. 🧬🔬 Learn more at www.aiffinity.com.

🚀 With fresh investment secured, we’re scaling up our software development team. We currently have two open positions. The successful candidates will contribute to the development of AI|ffinity's integrated NMR-AI platform.

Position Role: Structural Bioinformatics-NMR Software Developer
Brief Description: This role focuses on protein(-ligand) structure determination and includes:

  • Enhancing AI|ffinity’s 4D-GRAPHS software for automated chemical shift assignment. 4D-GRAPHS expands the applicability of protein NMR to proteins > 20 kDa and intrinsically disordered proteins.
  • Adapting transformer-based deep learning models for protein structure prediction (e.g., OpenFold, Chai-1, Boltz-1) to incorporate experimental restraints from NMR, SAXS, and Cryo-EM.
  • Establishing enhanced sampling molecular dynamics protocols for 3D structure ensemble generation using restraints from NMR, SAXS, and Cryo-EM experiments.
    For an overview of this technology, watch our YouTube videos.
    More information and applications at: https://lnkd.in/eG9Ffv8p

Position Role: Cheminformatics Developer
Brief Description: This role focuses on virtual screening, hit discovery, and hit-to-lead processes and includes:

  • Developing deep learning software solutions that leverage 1D and 2D NMR data to enhance drug design algorithm performance.
  • Providing computational and modeling support for drug discovery projects by applying AI|ffinity’s platform and other computer-aided drug design techniques to identify and develop small molecules in collaboration with industrial partners.
  • Developing processes and customizable workflows that can be adapted across the drug discovery portfolio.
    More information and applications at: https://lnkd.in/e25tjDyy

Thank you and best regards,
Thomas Evangelidis

 

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Dr. Thomas Evangelidis

CEO & CTO

AI|ffinity s.r.o.

www.aiffinity.com

Twitter: tevangelidis, LinkedIn: Thomas Evangelidis