PhD position available in MAS-DNP at CEA / Univ. Grenoble Alpes (France)

Interested in Dynamic Nuclear Polarization, method development, Helium MAS & instrumentation applied to challenging materials? Please contact me!gael.depaepe@cea.fr

More information about the lab and a list of recent publications can be found here: www.nmr-dnp-grenoble.net.

 

PhD topic: The PhD will focus on developing and applying ultra-low temperature fast MAS DNP in the 20 to 100 K range for the detection of low receptive nuclei. Our home-built setup (quasi-unique worldwide) is under continuous development and preliminary results show that it enables orders of magnitude of sensitivity gain compared to 100 K DNP measurements. During this PhD, we are planning to investigate new polarizing agents, Helium sample spinning beyond 20 kHz with a 3.2 mm rotor, and implement indirect detection approaches of low to ultra-low gamma nuclei (e.g. 17O, 43Ca). The methodology will be used to investigate the surface of ligand-capped ZnO nanocrystals and various calcium-phosphate biomaterials.

 

Location: Grenoble is one of the major cities in Europe for research with a large international scientific community. In addition, Grenoble has a large international student population, is a very pleasant city to live in, and is known as the “Capital of the Alps” with easy access to great skiing and hiking. It’s also only 2 hours’ drive to the Mediterranean Sea, Italy, or Switzerland. Grenoble, Lyon, and Geneva airports are nearby and permit straightforward international travel.

 

Benefits: Gross salary~ €2,500/month, health insurance, partial reimbursement of local transport expenses.

 

Applications: Candidates should hold a Master degree in physical chemistry, chemistry or physics. Interested candidates should send me a CV and a cover letter. Starting date around October 2024 – duration 3 years

 

Recent work for our group:

  1. Olejnik-Feher et al.(2024) On the Fate of Lithium Ions in Sol–Gel Derived Zinc Oxide Nanocrystals, SMALL, 2309984
  2. Paul et al. (2023). Sustainable and cost-effective MAS DNP-NMR at 30 K with cryogenic sample exchange, Journal of Magnetic Resonance356, 107561
  3. Kumar et al. (2023). Optimizing chemistry at the surface of prodrug-loaded cellulose nanofibrils with MAS-DNP. Communications Chemistry, 6(1), 58.
  4. Fu, et al. (2023). Solvent-derived defects suppress adsorption in MOF-74. Nature Communications, 14(1), 2386.
  5. Lee, et al. (2023). Revealing Electrolytic Ion Sorption in Layered Graphene Galleries through Low-Temperature Solid-State NMR. Chemistry of Materials, 35(10), 3841–3848.
  6. Halbritter et al. (2023). PyrroTriPol: a semi-rigid trityl-nitroxide for high field dynamic nuclear polarization. Chemical Science, 14(14), 3852–3864.
  7. Harrabi et al. (2022). Highly Efficient Polarizing Agents for MAS‐DNP of Proton‐dense Molecular Solids. Angewandte Chemie International Edition.https://doi.org/10.1002/anie.202114103
  8. Terlecki, et al. (2021), ZnO Nanoplatelets with Controlled Thickness: Atomic Insight into Facet-Specific Bimodal Ligand Binding Using DNP NMR,Advanced Functional Materials https://doi.org/10.1002/adfm.202105318

 

 

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Dr. Gaël De Paëpe

CEA Research Director

Interdisciplinary Research Institute of Grenoble (IRIG)

Modeling and Exploration of Materials Research Unit (MEM)

Head of the Magnetic Resonance laboratory (RM)

CEA / Univ. Grenoble Alpes

IRIG/MEM/RM - gael.depaepe@cea.fr

Voice (office) +33 4 38 78 65 70

Voice (lab)    +33 4 38 78 47 26

 

Mailing address:

CEA Grenoble

17 Avenue des Martyrs

Bâtiment 51C

Office P.132a / Lab P.138

38054 Grenoble

Cedex 9 - France