Two research grants @ Department of Chemistry, University of Torino

Dear colleagues,
We are looking for two team player and motivated postdoctoral fellows to join
our laboratory at the University of Turin in the frame of an Italian National
Ministry of University and Research granted project (MInO).
The two postdoctoral fellows will study the supramolecular interaction between
inorganic oxides and peptides/proteins and their mechanistic aspects by
combining NMR spectroscopy, microscopy, and molecular dynamics approaches. In
this frame, they will work on the interaction of soluble precursors of
inorganic oxides with proteins and peptides, in solution and in their
crystalline forms, as well as on the interaction of proteins and peptides with
the formed inorganic oxides using a multinuclear solid-state NMR (SS- NMR)
experiments set conducted at high field (600 MHz) at the University of Turin.
Solution NMR investigation will also be carried out to study the interaction
at molecular level in CERM at the University of Florence.
The project is a collaborative effort with Prof Enrico Ravera of CERM at the
University of Florence. We would like to develop an integrative approach to
explore the chemistry and biophysics of inorganic oxides forming peptides and
proteins to have mechanistic insights.
The candidates will be in charge of
(i) preparing NMR samples,
(ii) implementing and optimizing solution and solid/state NMR experiments,
(iii) analyzing the resulting data, together with Microscopy and Molecular
Dynamics results performed by our collaborator. They will be located at
Department of Chemistry at the University of Turin Italy.
The NMR facilities at the University of Turin and CERM are located in the two
well-known cities in Italy, and both provide a dynamic and international
working environment:
• University of Turin: our platform includes a state-of-the-art 600 MHz
equipped with solution and solid-state (1mm, 2.5mm, 3.2mm, and 4mm probes)
probes in order to provide a range of possibility from small molecules to very
large ones. Our platform also allows to study different NMR active nuclei
including 1 H, 11 B, 13 C, 15 N, 19 F, 23 Na, 27 Al, 29 Si and 31 P (in
principle observation of any NMR-active nucleus in the periodic table is
possible).
• CERM at University of Florence: unique access to first-class instrumentation
for structural biology such twelve high-resolution NMR spectrometers ranging
from 400 MHz to 1200 MHz are available for solution and solid-state NMR.
• The Instruct-ERIC and PANACEA networks will be solicited to access very fast
MAS probes at very high field (https://instruct-eric.org/,
https://panacea-nmr.eu/) when required by the project.
Applicants should have a Ph.D. and a strong experience in biomolecular NMR
(solution and/or solid-state). A specific focus on inorganic oxide formation
mediated by biological molecules will be
particularly appreciated. Experience in molecular modeling of the investigated
systems including interaction processes would be an advantage.
Any citizenship is welcome. The eligible candidate will be funded for 18
months by a grant from the Italian Research Ministry (PRIN grant MInO).
For information related to this job advertisement contact:
Dr Angelo Gallo; angelo.gallo@unito.it
Prof Enrico Ravera; enrico.ravera@unifi.it
Best regards
Dr Angelo Gallo