Master and PhD positions in Protein Solid-State NMR at Lyon University/CNRS

Dear students, dear colleagues,

we are seeking to fill Master 2 and PhD student positions in our lab, for work in human viral (membrane) protein solid-state NMR. We are looking for motivated and enthusiastic students  in chemistry, biochemistry or biophysics, and interest in NMR to join our dynamic and international team. We offer a friendly and collaborative working environment  (

Our Institute (MMSB) s a mixed CNRS/Lyon University Unit, located on the Biosciences campus, in close proximity to the city center. MMSB is equipped with a complete state-of-the-art array of biochemistry/molecular biology facilities for cloning, expression and purification of proteins, and has access to several high-field NMR spectrometers at the CRMN Lyon. Access is facilitated to a number of state-of-the-art research platforms as well. (

Techniques used include biochemical methods, including cell-free protein expression with isotopic markers, nuclear magnetic resonance (NMR) and also electron microscopy. The student will be involved in protein production, NMR spectra recording and analysis. S/he will be supervised by the team members involved in the project.

Lyon is a beautiful and highly attractive city, the second largest in France, with excellent connections to Paris, Marseille, and the Alps (

If you have any further questions, please do not hesitate to contact us. If you are interested, please send your CV and cover letter to


Lecoq, Lauriane, Louis Brigandat, Rebecca Huber, Marie-Laure Fogeron, Shishan Wang, Marie Dujardin, Mathilde Briday, et al. « Molecular Elucidation of Drug-Induced Abnormal Assemblies of the Hepatitis B Virus Capsid Protein by Solid-State NMR ». Nature Communications 14, no 1 (28 janvier 2023): 471.


Briday, Mathilde, François Hallé, Lauriane Lecoq, Sylvie Radix, Juliette Martin, Roland Montserret, Marie Dujardin, et al. « Pharmacomodulation of a Ligand Targeting the HBV Capsid Hydrophobic Pocket ». Chemical Science, 2022, 10.1039.D2SC02420A.


Callon, Morgane, Alexander A. Malär, Lauriane Lecoq, Marie Dujardin, Marie-Laure Fogeron, Shishan Wang, Maarten Schledorn, et al. « Fast Magic-Angle-Spinning NMR Reveals the Evasive Hepatitis B Virus Capsid C-Terminal Domain ». Angewandte Chemie International Edition 61, no 32 (2022): e202201083.


Fogeron, Marie-Laure, Lauriane Lecoq, Laura Cole, Matthias Harbers, et Anja Böckmann. « Easy Synthesis of Complex Biomolecular Assemblies: Wheat Germ Cell-Free Protein Expression in Structural Biology ». Frontiers in Molecular Biosciences 8 (25 mars 2021): 639587.


Lecoq, Lauriane, Shishan Wang, Marie Dujardin, Peter Zimmermann, Leonard Schuster, Marie-Laure Fogeron, Mathilde Briday, et al. « A Pocket-Factor–Triggered Conformational Switch in the Hepatitis B Virus Capsid ». Proceedings of the National Academy of Sciences 118, no 17 (27 avril 2021): e2022464118.